What are the side effects of baclofen?

With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

Contact your doctor immediately if you experience any of the following:

  • Seizures
  • Allergic reactions

The following side effects may get better over time as your body gets used to the medication. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time.

Common side effects

  • Drowsiness (up to 63%)
  • Dizziness (up to 15%)
  • Weakness (up to 15%)
  • Nausea (up to 12%)
  • Confusion (up to 11%)

Other side effects

  • Headache
  • General feeling of low energy
  • Constipation
  • More frequent urination
  • Low blood pressure
  • Trouble sleeping
  • Ovarian cyst (fluid filled sac on your ovary)

The following side effects have also been reported:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare

Bloody or dark urine

chest pain


mental depression or other mood changes

ringing or buzzing in the ears

seeing or hearing things that are not there

skin rash or itching

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Blurred vision


difficult or troubled breathing



irregular, fast or slow, or shallow breathing


loss of strength or energy

muscle pain or weakness

pale or blue lips, fingernails, or skin

sleepiness or unusual drowsiness

unusual weak feeling

unusually slow or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common



dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


increased need to urinate


passing urine more often


trouble sleeping

unusual tiredness or weakness

Less common or rare

Abdominal or stomach pain or discomfort

clumsiness, unsteadiness, trembling, or other problems with muscle control


false sense of well-being

loss of appetite

muscle or joint pain

numbness or tingling in the hands or feet

pounding heartbeat

slurred speech or other speech problems

stuffy nose

swelling of the ankles

unexplained muscle stiffness

unusual excitement

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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